Clinical immunology made ridiculously simple editor 3

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A well-developed knowledge of clinical microbiology is
critical for the practicing physician in any medical field.
Bacteria, viruses, and protozoans have no respect for
the distinction between ophthalmology, pediatrics,
trauma surgery, or geriatric medicine. As a physician
you will be faced daily with the concepts of microbial
disease and antimicrobial therapy. Microbiology is one
of the few courses where much of the "minutia" is regularly
used by the practicing physician.
This book attempts to facilitate the learning of microbiology
by presenting the information in a clear and
entertaining manner brimming with memory aids.
Our approach has been to:

1) Write in a conversational style for rapid assimilation.
2) Include numerous figures serving as "visual memory
tools" and summary charts at the end of each chapter.
These can be used for "cram sessions" after the
concepts have been studied in the text.
3) Concentrate more on clinical and infectious disease
issues that are both interesting and vital to the actual
practice of medicine.

4) Create a conceptual, organized approach to the organisms

studied so the student relies less on memory

and more on logical pathophysiology.

The text has been updated to include current information

on rapidly developing topics, such as HIV and

AIDS (vaccine efforts and all the new anti-HIV medications),

Ebola virus, Hantavirus, E. coli outbreaks, Mad

Cow Disease, and brand-new antimicrobial antibiotics.

The mnemonics and cartoons in this book do not intend

disrespect for any particular patient population or

racial or ethnic group but are solely presented as memory

devices to assist in the learning of a complex and important

medical subject.

We welcome suggestions for future editions.

MARK GLADWIN, MD
BILL TRATTLER, MD

PART 1

1 BACTERIAL TAXONOMY 1
2 CELL STRUCTURES, VIRULENCE FACTORS, and TOXINS 8
3 BACTERIAL SE( GENETICS 16
GRAM-POSITIVE BACTERIA 22
4 STREPTOCOCCUS 22
5 STAPHYLOCOCCUS 31
6 BACILLUS and CLOSTRIDIUM (SPORE-FORMING RODS) 38
7 CORYNEBACTERIUM and LISTERIA (NON-SPORE-FORMING RODS) 45
GRAM-NEGATNE BACTERIA 49
8 NEISSERIA 49
9 THE ENTERICS 54
10 HAEMOPHILUS, BORDETELLA, and LEGIONELLA 68
11 YERSINIA, FRANCISELLA, BRUCELLA, and PASTEURELLA 73
12 CHLAMYDIA, RICKETTSIA, and FRIENDS 78
13 SPIROCHETES 91
ACID-FAST BACTERIA 102
14 MYCOBACTERIUM 102
BACTERIA WITHOUT CELL WALLS 111
15 MYCOPLASMA 111
ANTI-BACTERIAL MEDICATIONS 114
16 PENICILLIN FAMILY ANTIBIOTICS 114
17 ANTI-RIBOSOMAL ANTIBIOTICS 125
18 ANTI-TB and ANTI-LEPROSY ANTIBIOTICS 133
19 MISCELLANEOUS ANTIBIOTICS 139

PART 2. FUNGI

20 THE FUNGI 144
21 ANTI-FUNGAL MEDICATIONS 155

PART 3

22 VIRAL REPLICATION and TAXONOMY 161
23 ORTHOMYXO and PARAMYXOVIRIDAE 172
24 HEPATITIS VIRIDAE 180
25 RETROVIRIDAE, HIV, and AIDS 190
26 HERPESVIRIDAE 204
27 REST OF THE DNA VIRUSES 209
28 REST OF THE RNA VIRUSES 214
29 ANTI-VIRAL MEDICATIONS 224

PART 4. PARASITES

30 PROTOZOANS 231
31 HELMINTHS

PART 5

32 PRIONS (contributing author: Hans Henrik Larsen, M.D.) 265

PART 6.

33 ANTIMICROBIAL RESISTANCE: ONE STEP TOWARD THE POST-ANTIBIOTIC ERA?
(contributing author: Earnest Alexander, Pharm.D.)

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